Mooney then scored her century with three balls left and reached 106 not out.
โIt was a pleasure to be out there with her,โ Mooney told Channel 7.
โIโve seen that a few times in her career … wherever they bowl the ball she seems to find a way to get the ball to the ropes.
โTo finish like that I hope she looks back and is really proud of her career. To be able to do that in her last ODI is unreal.โ
Healy also bowled two overs when the result was beyond doubt, but her gentle finger spin did not threaten the Indians and she remains without an international wicket.
โIt didnโt take much to get talked into (bowling) – I heard my name mentioned once and I said โrightoโ,โ Healy joked.
The Indians formed a guard of honour for Healyโs last ODI innings, with the opener retiring from all cricket after the Perth Test.
Healy started cramping in the 80s, but that only seemed to fire her up more. The 35-year-old great belted 27 fours and two sixes in her 98-ball masterclass.
It was her eighth one-day international ton, equalling Karen Rolton and behind only Meg Lanningโs 15 as the most by an Australian.
Not to be outdone, Beth Mooney also delivered a century for Australia.Credit: Getty Images
She was bowled trying a trick shot off an innocuous full toss from Sneh Rana, just 12 runs shy of her highest one-day international score.
Georgia Voll continued her excellent form with 62 in a second-wicket stand of 104 with Healy. Mooney then joined the pile-on in a 145-run partnership with her skipper.
No.9 Nicola Carey belted an unbeaten 34 from 15 balls after Australia lost three quick wickets to help Mooney finish off the innings and ensure they passed 400.
Mooney only needed 84 balls for her century, hitting 10 fours and a six.
Rana and Sree Charani took two wickets apiece.
India posted a record 5-341 to beat Australia in last Octoberโs World Cup semi-final.
But in-form opener Smriti Mandhana made a fourth-ball duck on Sunday night to immediately put India on the back foot.
Healy sweeps with precision.Credit: Getty Images
Leg-spinner Alana King took 4-33 from 10 overs, including the crucial wicket of Indian captain Harmanpreet Kaur.
King trapped Kaur lbw with an excellent straight ball for 25, leaving India 5-115 and no chance of a miracle. Jemima Rodrigues made 42 at No.3 to lead the early challenge before she top-edged Ashleigh Gardner to debutant Lucy Hamilton at fine leg.
Hamilton opened the bowling with her left-arm pace. She โbadgedโ Deepti Sharma on the helmet with a bouncer, but the No.6 was able to keep batting and made 29, while Rana top-scored with 44.
Earlier on Sunday, Cricket Australia announced that the womenโs tour of the West Indies this month will not feature a Test – only three T20s and three ODIs.
AUSTRALIA: Alyssa Healy (capt), Phoebe Litchfield, Georgia Voll, Beth Mooney (wk), Annabel Sutherland, Ashleigh Gardner, Tahlia McGrath, Georgia Wareham, Nicola Carey, Alana King, Lucy Hamilton
INDIA: Smriti Mandhana, Pratika Rawal, Harleen Deol, Harmanpreet Kaur (capt), Jemimah Rodrigues, Richa Ghosh (wk), Deepti Sharma, Kashvee Gautam, Sree Charani, Sneh Rana, Renuka Singh Thakur.
