Pope Leo XIV is scheduled to have an operation this week to remove โa localized noduleโ in his lung that was โdetected at a very early stage.โ It is the first medical event of his 17-month papacy.
The Vatican said he will be admitted to Romeโs Gemelli hospital on Tuesday, and predicted a weeklong recovery.
Here is what is known:
A nodule can be benign or malignant
A lung nodule is a small abnormal area measuring less than three centimeters (about 1.2 inches) across. It is sometimes detected on a CT scan performed to investigate another problem, such as trauma or a lung infection, according to the American Cancer Society.
Experts say the nodule could be benign or malignant and that prompt evaluation is important.
If the nodule is cancerous and removed at an early stage, the prognosis is โexcellent,โ and surgery alone may be sufficient treatment, said Dr. Stephen Liu, a lung cancer expert at Georgetownโs Lombardi Comprehensive Cancer Center.
Leo, 71, is considered otherwise healthy and physically fit, both positive factors for his recovery. He said the nodule was discovered during โrecent medical tests,โ and the Vatican said Monday that no particular health issue prompted the check-up, describing it as โroutine.โ
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Surgery followed by a week of recovery
The Vatican said Leo will be admitted to the hospital on Tuesday in the late morning and undergo surgery in the first days of this week. Oncologists who arenโt treating him said patients can often be discharged after just a few days, to recover further at home.
The exact date of surgery wasnโt released, but Leo had a full slate of audiences and appointments Monday morning and afternoon.
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The pope will be treated at Romeโs Gemelli hospital, formally known as the Agostino Gemelli Polyclinic, a non-profit Catholic teaching hospital that is part of the Catholic Sacred Heart University.
The facility has a special apartment set up for pontiffs on the 10th floor that includes a private chapel. Leoโs immediate predecessor, Pope Francis, was treated there before his May 2025 death during a long illness prompted by a respiratory crisis.
St. John Paul II spent so much time at Gemelli that he called it โVatican III,โ after the Vatican itself and the papal summer residence at Castel Gandolfo.
Upcoming activities and trip in question
Leo has several activities scheduled this week.
In addition to his regular meetings, he was due to celebrate a public Mass on Wednesday to close a weeklong conference on family ministry. It wasnโt known if someone else would celebrate the Mass.
Leo also has a major trip planned Nov. 6-17 to Uruguay, Argentina and Peru. It is unclear whether the surgery and recovery will affect the ambitious itinerary, which includes a dozen flights, two helicopter rides and significant altitude changes in Peru. Leo said earlier in his remarks Sunday that he still planned to make the trip.
Pope remains in charge, even when unconscious
The Vatican has no specific rules governing who takes over if a pope becomes totally incapacitated. Even while unconscious during surgery, Leo remains pope and retains his authority.
Pope Francis remained in charge throughout his lengthy hospitalizations, as did St. John Paul II before him. Both made appointments and issued laws and statements from the hospital. A team of officials already handles day-to-day Vatican operations.
Medical advances and popesโ longer lifespans, however, have highlighted this gap in church law and prompted calls for the Vatican to prepare for a pope becoming too ill or incapacitated to govern.
Two days before revealing his planned surgery, Leo confirmed one significant appointment.
On Friday, he approved Filipino Cardinal Luis Antonio Tagle as the new dean of the College of Cardinals. Tagle, 69, replaces Cardinal Giovanni Battista Re, 92, whose term Francis extended in the weeks before his death.
The dean plays a significant role in a papal transition. He presides over the previous popeโs funeral and helps lead the cardinalsโ closed-door meetings before the conclave to discuss the churchโs future needs. If he is under 80 when the conclave begins, he also presides over the secret election of a new pope in the Sistine Chapel.
The Vatican released a letter Leo wrote to Re on Sunday โ the day of his announcement โ thanking him for his lifelong service to the church. He noted in particular the role that Re played in the recent papal transition, when he celebrated Francisโ funeral.
โI do not think I am mistaken in saying that you, Your Eminence, have been and remain one of the Holy Seeโs best-known and most esteemed servants,โ Leo wrote.
© 2026 The Canadian Press
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